Unlocking the power of Probiotics: success stories from Denmark and Brazil

Published on 25-10-2024 - Written by Kemin Animal Nutrition and Health

In the dynamic world of animal production, one word is gaining considerable attention: probiotics. While the term may sound more at home in a health food store than a pig farm, probiotics are revolutionizing the way pigs are raised, particularly in Europe.

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What are Probiotics?

In simpler terms, they're the good bacteria that support digestive health and overall well-being. This means improved resilience to enteric bacterial pathogens, enhanced nutrient absorption, and stronger immune systems for pigs.

Which actions are the most desirable one?

There are different options, such as live yeast or bacteria. Some of them have a wider spectrum than others. We have found that the most successful strategies contained probiotics made of bacteria spores which:

  • Produce antibacterial metabolites, which break the membrane of the bacteria, causing its death.
  • Produce molecules which interfere with bacterial communication systems – this is called quorum quenching.
  • Support the growth of beneficial bacteria – not all bacteria are detrimental!
  • All in all, improves microbial diversity.

Danish Experience- Almost 2000 small piglets say yes to an alternative diet:

This project aimed to evaluate a brand-new diet for more miniature piglets. This can be interesting for farms that can get two different feeds and feed the bottom 10-15% of the piglets differently. Alternatively, it could be helpful for bigger companies with multiple farms which know the farms that consistently wean lighter piglets, they could use a diet like this one

Set up

  • 1072 small piglets weaned at 25 days old where selected.
    • Control group 538 piglets at 4.2 kg
    • Test group 534 at 4.1 kg
    • No significant differences in weight at weaning weight
  • The study was performed by TestPig at the Skjoldborg test station, and diets were formulated by the Danish Pig Advisory Service.
  • The control group had a diet with 3000ppm of Zinc oxide.
  • The test group had a diet with lower energy and crude protein level (16.1% CP) and it was supplemented
    • Encapsulated Organic Acids and Nature Compound 4kg/t
    • Probiotic: Bacillus sp. PB6 750g/t
    • Organic acids via water
  • Both Groups had 0.5% of Benzoic Acid and Calcium Formate
  • All piglets were fed either the test or control diet for 14 days post weaning only, after 14 days they were moved to a different room and transition within the first 3 days to the regular diet for the farm.
  • Feed intake, Average Daily Gain, Feed Conversion Rate, mortality, and treatments were recorded. In addition, the number of days on which 1/3, 2/3, or 3/3 of the pen had diarrhoea was recorded.

Results

  • There was no significant difference in the days with diarrhoea between the control group and the test group.
  • Additionally, the test group had a better Feed Conversion rate of 1.51 in the control group vs. 1.4 in the test diet p<0.001. Refer to Table 1
  • Although the diet was fed only for 14 days, it had a carry-over effect, reducing the Feed conversion rate significantly, proving that an alternative diet for small piglets is worth it.
  • To confirm the trial, results were later evaluated in 3 farms with 400, 120 and 250 piglets with similar or better results than the original trial.

Table 1

   

Experimental group

P-values

LSD

 

Day

ZnO diet

Reformulated diet
(FormaXOL + CLOSTAT)

Diet

BW x diet

Body weight

           

Initial body weight (kg/pig)y

1

4.2 (±0.5)

4.1 (±0.6)

na

na

na

Intermediary body weight (kg/pig)y

14

6.6 (±0.8)

6.9 (±0.8)

na

na

na

Final Body weight (kg/pig)y

43

22.8 (±1.8)

22.6 (±2.0)

na

na

na

             

1-14 days after weaning

           

ADG (g/d/pig)x

1-14

173

198

0.13

0.007

37

FI (g/d/pig)x

1-14

265

275

0.53

ns

36

FCRx

1-14

1.51

1.40

0.03

<0.001

0.16

1-43 days after weaning

           

ADG (g/d/pig)x

1-43

427

424

0.85

ns

 

FI (g/d/pig)x

1-43

620

599

0.32

ns

57

FCRx

1-43

1.44

1.38

0.03

ns

80

Brazilian Experience – successfully replacing antibiotic with probiotics in the post weaning phase

In collaboration with Federal university of Lavras

Set up

  • 240 weaned pigs at 23 days old with an average weaning weight of 6.7kg.
  • 120 piglets were fed the control diet with antibiotics and 120 piglets the treatment diet with Bacillus sp. PB6.
 

Phase

Control

Bacillus sp. PB6

Treatments

 

Pre-Starter 1 (24-31days old)

Flavomicin (12 PPM)

500 g / t

Pre-Starter 2 (31 to 38 days old)

Flavomicin (12 PPM)

500 g / t

Starter 1 (39 to 45 days old)

Enramicin (12 PPM)

500 g / t

Starter 2 (46 to 72 days old)

Enramicin (12 PPM)

500 g / t

   
  • Piglets were weighed at the end of each phase; feed consumption was monitored.
  • Diarrhoea was also scored (1 to 5 with 1 being the lowest incidence).

Results

  • The pre-starter 1 phase is crucial as pigs have just been weaned, and we want them to be eaten as soon as possible. We have noticed a significant increase in average daily gain (ADG, 19% p<0.01), a 12% improvement in feed conversion ratio (FCR) p<0.05, and a higher feed intake 6% more p<0.05.
  • A summary of the pre started phase 1 can be seen below
TabelPic
  • No significant differences were observed throughout the nursery period, which is positive as we can replace an antibiotic therapy option with probiotics.
  • In addition, the total cost of feeding a piglet with the control diet cost €11.97 and the probiotic alternative 11.85€ (at the time of the trial). Thus, we can save 12 cents per pig in a sustainable way!

As the global demand for pork continues to rise, so does the need for sustainable and ethical farming practices. Probiotics offer a promising solution, promoting animal welfare while simultaneously benefiting the bottom line.